[The curative effect of rhubarb extract on severe periodontitis in patients with diabetes mellitus].
Shanghai Kou Qiang Yi Xue. 2018 Dec ;27(6):633-636. PMID: 30899946
PURPOSE: To observe the curative effect of rhubarb extract on severe periodontitis in patients with diabetes mellitus.
METHODS: Fifty patients with severe periodontitis and diabetes mellitus were randomly divided into 2 groups. The patients in the control group were treated with scaling and root planning(SRP); while patients in the experimental group were treated with SRP followed by topical use of rhubarb extract. Periodontal index probing pocket depth (PD), clinical attachment level (CAL) and bleeding on probing (BOP) were examined before periodontal treatment，6 weeks and 12 weeks after treatment. SPSS 20.0 software package was used for statistical analysis.
RESULTS: Significant improvement in periodontal condition was noted in both groups after treatment, and the degree of improvement was greater in the experimental group than in the control group. No adverse event during the entire study was found.
CONCLUSIONS: Topical application of rhubarb extract for the treatment of severe periodontitis with diabetes has good clinical efficacy.