Abstract Title:

Curcumin-artemisinin combination therapy for malaria.

Abstract Source:

Antimicrob Agents Chemother. 2006 May;50(5):1859-60. PMID: 16641461

Abstract Author(s):

Dalavaikodihalli Nanjaiah Nandakumar, Viswanathan Arun Nagaraj, Palakkod Govindan Vathsala, Pundi Rangarajan, Govindarajan Padmanaban

Article Affiliation:

Department of Biochemistry, Indian Institute of Science, Bangalore 560 012, India.


Artemisinin and curcumin show an additive interaction in killing Plasmodium falciparum in culture. In vivo, 3 oral doses of curcumin following a single injection of alpha,beta-arteether to Plasmodium berghei-infected mice are able to prevent recrudescence due to alpha,beta-arteether monotherapy and ensure almost 100% survival of the animals.

Study Type : Animal Study

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