Curcumin has trypanocidal properties. - GreenMedInfo Summary

Abstract Title:

Trypanocidal effects of curcumin in vitro.

Abstract Source:

Biol Pharm Bull. 1998 Jun;21(6):643-5. PMID: 9657056

Abstract Author(s):

M Nose, T Koide, Y Ogihara, Y Yabu, N Ohta

Article Affiliation:

Department of Pharmacognosy and Plant Chemistry, Faculty of Pharmaceutical Sciences, Nagoya City University, Japan.


During the course of study searching for the antiparasitic agents from natural compounds, we found that curcumin showed cytotoxicity against African trypanosomes in vitro. The LD50 values of curcumin were 4.77 +/- 0.91 microM for bloodstream forms and 46.52 +/- 4.94 microM for procyclic forms of Trypanosoma brucei brucei (GUTat 3.1 clone).

Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Trypanocidal Agents : CK(2) : AC(2)

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