Cutaneous vasculitis associated with interferon beta-1b treatment for multiple sclerosis.
Clin Neuropharmacol. 2009 Sep-Oct;32(5):301-3. PMID: 19820436
Department of Neurology, Faculty of Medicine, Safarik University, Kosice, Slovakia. email@example.com
We report a 38-year-old woman with relapsing-remitting multiple sclerosis, treated with subcutaneous injections of interferon beta (IFN-beta)-1b every other day. Disseminated cutaneous lesions were observed after 3 injections. These symptoms reappeared after drug readministration. The histopathological examination of the skin specimens confirmed nonspecific cutaneous lymphocytic vasculitis. The patient's outcome was favorable after corticosteroid placement and discontinuing IFN-beta therapy. Isolated lymphocytic cutaneous vasculitis linked to IFN-beta-1b therapy is suspected as a new association.