Data on spermatogenesis in rat males gestationally exposed to bisphenol A and high fat diets - GreenMedInfo Summary
Data on spermatogenesis in rat males gestationally exposed to bisphenol A and high fat diets.
Data Brief. 2016 Dec ;9:812-817. Epub 2016 Nov 2. PMID: 27872877
This data article contains supporting information regarding the research article entitled"High butter-fat diet and bisphenol A additively impair male rat spermatogenesis"(P. Tarapore, M. Hennessy, D. Song, J. Ying, B. Ouyang, V. Govindarajah, et al.,) . Sprague-Dawley females were fed AIN, high fat butter, 17α-ethinyl estradiol, or high fat butter plus four bisphenol A doses (2500 µg/kg bw-d, 250 µg/kg bw-d, 25 µg/kg bw-d, and 2.5 µg/kg bw-d) before and during pregnancy. All diets were switched to AIN after the pups were born. Male offspring received testosterone (T)- and estradiol-17β (E2)-filled implants from postnatal day 70-210 for 20 weeks (T+E2 rat model). The testes were weighed, and examined for impairments in spermatogenesis.