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Abstract Title:

Vitamin D deficiency and suicidal ideation: A cross-sectional study of 157,211 healthy adults.

Abstract Source:

J Psychosom Res. 2020 Apr 25 ;134:110125. Epub 2020 Apr 25. PMID: 32388454

Abstract Author(s):

Sun-Young Kim, Sang-Won Jeon, Weon-Jeong Lim, Kang-Seob Oh, Dong-Won Shin, Sung Joon Cho, Jae-Hyun Park, Young Hwan Kim, Young-Chul Shin

Article Affiliation:

Sun-Young Kim

Abstract:

OBJECTIVES: Vitamin D deficiency has been reported to be associated with various neuropsychiatric disorders. However, there are few studies addressing deficient vitamin D levels and suicidal ideation.

METHODS: Serum vitamin D of 157,211 Korean adult participants were measured using electrochemiluminescence immunoassay. A self-reported questionnaire was used to assess whether participants experienced suicidal ideation. Logistic regression model was used to estimate the odds ratio (OR) of suicidal ideation according to vitamin D levels. The regression was adjusted for a range of covariates.

RESULTS: Compared with sufficient vitamin D levels (≥20 ng/mL), deficient vitamin D levels (<10 ng/mL) were significantly associated with the risk of suicidal ideation (OR = 1.138, 95% Cl = 1.027-1.262). However, the OR of suicidal ideation was not significantly different between the vitamin D insufficient group (10-19.99 ng/mL) and sufficient group (≥20 ng/mL) (OR = 0.988, 95% Cl = 0.932-1.047).

CONCLUSION: Deficient vitamin D levels were significantly associated with the risk of suicidal ideation. However, the risk of suicidal ideation was not significantly different between the vitamin D insufficient group and sufficient group.

Study Type : Human Study

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Sayer Ji
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