Abstract Title:

Delay of diethylnitrosamine-induced hepatoma in rats by carrot feeding.

Abstract Source:

Oncology. 1983 ;40(2):120-3. PMID: 6828289

Abstract Author(s):

A Rieder, M Adamek, H Wrba


Carcinogenesis and death caused by diethylnitrosamine(DENA)-induced hepatomas in Sprague Dawley rats can be significantly delayed by feeding only carrots for several days a week. As this result is not obtained by supplementing food with even higher concentrations of synthetic beta-carotene, there must be several other factors which--together with the carotenoid--contribute to the positive effect. Several other possibilities such as effects of fasting, direct interactions with the carcinogen, resorption, vitamin A storage in the liver, etc., are proposed and discussed.

Study Type : Animal Study

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