Abstract Title:

Delphinidin prevents disuse muscle atrophy and reduces stress-related gene expression.

Abstract Source:

Biosci Biotechnol Biochem. 2016 Aug ;80(8):1636-40. Epub 2016 May 16. PMID: 27180787

Abstract Author(s):

Motoki Murata, Reia Kosaka, Kana Kurihara, Shuya Yamashita, Hirofumi Tachibana

Article Affiliation:

Motoki Murata


Delphinidin is a member of the anthocyanidin class of plant pigments. We examined the effects of delphinidin on muscle atrophy. Oral administration of delphinidin suppressed the muscle weight loss induced by mechanical unloading. Microarray analysis showed that delphinidin suppresses the upregulation of oxidative stress-related gene expression, including the expression of Cbl-b. Thus, delphinidin may prevent unloading-mediated muscle atrophy.

Study Type : In Vitro Study

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