Determination of Mineral Composition and Phenolic Content and Investigation of Antioxidant, Antidiabetic, and Antibacterial Activities ofL. Aqueous Stigmas Extracts.
Adv Pharmacol Pharm Sci. 2021 ;2021:7533938. Epub 2021 May 29. PMID: 34195613
The aim of this study is to investigate theantioxidant, antidiabetic, and antibacterial activities of Moroccan and Italian(L.) stigmas extracts. The antioxidant activity was evaluated by DPPH radical scavenging assay, and the results showed that the Moroccan extract has a powerful antioxidant activity with an ICof 0.32 ± 0.059 g/mL compared to the Italian extract (ICof 3.14 ± 0.021 g/mL). Additionally, the antidiabetic activity was evaluated by using alpha-amylase and alpha-glucosidase inhibition assay, and both extracts showed significant antidiabetic activity. However, the antibacterial activity was evaluated by the disc diffusion method to determine the inhibitory diameters and microplate dilutions method to determine the minimum inhibitory concentration. Our findings revealed that both Moroccan and Italian extracts were more effective against Gram-positive than Gram-negative bacteria. From this study, we can conclude that the studied extracts ofare rich in natural compounds and could have a broad application in the pharmaceutical, food, and medical fields.