Article Publish Status: FREE
Abstract Title:

Aqueous Extract of Anethum Graveolens L. has Potential Antioxidant and Antiglycation Effects.

Abstract Source:

Iran J Med Sci. 2016 Jul ;41(4):328-333. PMID: 27365555

Abstract Author(s):

Ebrahim Abbasi Oshaghi, Iraj Khodadadi, Heidar Tavilani, Mohammad Taghi Goodarzi

Article Affiliation:

Ebrahim Abbasi Oshaghi

Abstract:

The aim of this study was to assess the antiglycation and antioxidant properties of aqueous extract of Anethum graveolens (dill). In the in vivo and in vitro experiments, antioxidant properties, blood glucose, and AGEs formation were determined. Dill extract was given orally to healthy and diabetic rats. Our results illustrated that different concentrations of dill extract (0.125, 0.25, 0.5, and 1 mg/ml) have potential antiradical and antioxidant activity. Aqueous extract of dill significantly reduced AGEs formation and fructosamine levels, protein carbonyl and also thiol group's oxidation, amyloid cross-β and fragmentation. After 2 months, blood glucose levels (P=0.006) and AGEs formation (P=0.003) significantly reduced in dill treated group compared with untreated diabetic animals. In conclusion, dill can be recommended as herbal medicine for the control and prevention of diabetic complications.

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