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Abstract Title:

Micronized diosmin (Detralex) for vein-related trophic ulcers: European experience.

Abstract Source:

Angiol Sosud Khir. 2006;12(3):53-60. PMID: 17641615

Abstract Author(s):

V S Savel'ev, A V Pokrovskiĭ, S V Sapelkin, V Iu Bogachev, L I Bogdanets, I A Zolotukhin

Abstract:

The paper presents a meta-analysis of 5 large European studies (N - 723) on the micronized diosmin administration to patients with venous trophic ulcers (CEAP class VI). With the use of evidence-based approach, it was shown that micronized diosmin has a statistically significant clinical effect on middle-sized trophic ulcers (5 - 10 cm(2)) that persisted for 6 - 12 months. The study concludes that polyvalent venotonics are an appropriate and valuable addition to complex therapy of complicated chronic venous insufficiency..

Study Type : Review

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