Article Publish Status: FREE
Abstract Title:

An Early, Universal Mediterranean Diet-Based Intervention in Pregnancy Reduces Cardiovascular Risk Factors in the"Fourth Trimester".

Abstract Source:

J Clin Med. 2019 Sep 19 ;8(9). Epub 2019 Sep 19. PMID: 31546914

Abstract Author(s):

Carla Assaf-Balut, Nuria Garcia de la Torre, Alejandra Durán, Elena Bordiu, Laura Del Valle, Cristina Familiar, Johanna Valerio, Inés Jimenez, Miguel Angel Herraiz, Nuria Izquierdo, Isabelle Runkle, María Paz de Miguel, Carmen Montañez, Ana Barabash, Martín Cuesta, Miguel Angel Rubio, Alfonso Luis Calle-Pascual

Article Affiliation:

Carla Assaf-Balut


An early antenatal dietary intervention could play an important role in the prevention of metabolic diseases postpartum. The aim of this study is to evaluate whether an early, specific dietary intervention reduces women's cardiovascular risk in the"fourth trimester". This prospective cohort study compares 1675 women from the standard-care group (ScG/n = 676), who received standard-care dietary guidelines, with the intervention group (IG/n = 999), who received Mediterranean diet (MedDiet)-based dietary guidelines, supplemented with extra-virgin olive oil and nuts. Cardiovascular risk was determined by the presence of metabolic syndrome (MetS) and insulin resistance syndrome (IrS) (HOMA-IR 3.5) at 12-14 weeks postpartum. MetS was less frequent in the IG (11.3 vs. 19.3%,<0.05). The intervention was associated with a reduction in the relative risk of having MetS: 0.74 (95% CI, 0.60-0.90), but not in the risk of IrS. When analyzing the presence of having one or more components of the MetS, the IG had significantly higher rates of having 0 components and lower rates of having≥1 (-trend = 0.029). An early MedDiet-based nutritional intervention in pregnancy is associated with reductions in postpartum rates of MetS.

Study Type : Human Study

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