n/a
Abstract Title:

Eczema vaccinatum resulting from the transmission of vaccinia virus from a smallpox vaccinee: an investigation of potential fomites in the home environment.

Abstract Source:

Vaccine. 2009 Jan 14 ;27(3):375-7. Epub 2008 Nov 21. PMID: 19027813

Abstract Author(s):

Edith Lederman, Roque Miramontes, John Openshaw, Victoria A Olson, Kevin L Karem, John Marcinak, Rodrigo Panares, Wayne Staggs, Donna Allen, Stephen G Weber, Surabhi Vora, Susan I Gerber, Christine M Hughes, Russell Regnery, Limone Collins, Pamela S Diaz, Mary G Reynolds, Inger Damon

Article Affiliation:

Edith Lederman

Abstract:

On March 3, 2007, a 2-year-old boy was hospitalized with eczema vaccinatum. His two siblings, one with eczema, were subsequently removed from the home. Swabs of household items obtained on March 13th were analyzed for orthopoxvirus DNA signatures with real-time PCR. Virus culture was attempted on positive specimens. Eight of 25 household samples were positive by PCR for orthopoxvirus; of these, three yielded viable vaccinia virus in culture. Both siblings were found to have serologic evidence of orthopoxvirus exposure. These findings have implications for smallpox preparedness, especially in situations where some household members are not candidates for vaccination.

Study Type : Human: Case Report
Additional Links
Additional Keywords : Vaccine Shedding : CK(31) : AC(4)
Anti Therapeutic Actions : Vaccination: Smallpox : CK(74) : AC(9)

Print Options


Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2020 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.