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Abstract Title:

Effect of pea protein plus grape seed dry extract on a murine model of Candida albicans induced vaginitis.

Abstract Source:

Future Microbiol. 2018 09 ;13:1375-1382. Epub 2018 Sep 26. PMID: 30256168

Abstract Author(s):

Emanuela Esposito, Michela Campolo, Giovanna Casili, Marika Lanza, Alessia Filippone, Alessio F Peritore, Salvatore Cuzzocrea

Article Affiliation:

Emanuela Esposito

Abstract:

AIM: The objective of this research was to evaluate the antifungal properties of the association between grape seed and pea by using a nonpharmacological medical device that contains them.

MATERIALS & METHODS: A murine model of vulvovaginal candidiasis, induced by Candida albicans infection, was used.

RESULTS: We showed that topical treatment with the device significantly reduced the fungal burden in vagina and preserved vagina tissue architecture from C. albicans infection.

CONCLUSION: We can support the potential beneficial effect of the association between grape and pea extract present in the medical device. Together these results supported this device as a favorable antifungal agent and a promising synergist with fluconazole in the clinical management of vulvovaginal candidiasis caused by C. albicans biofilms.

Study Type : Animal Study

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Sayer Ji
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