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Abstract Title:

Enhanced anti-influenza A virus activity of (-)-epigallocatechin-3-O-gallate fatty acid monoester derivatives: effect of alkyl chain length.

Abstract Source:

Nutr Cancer. 2010 Aug;62(6):789-94. PMID: 18547804

Abstract Author(s):

Shuichi Mori, Shinya Miyake, Takayoshi Kobe, Takaaki Nakaya, Stephen D Fuller, Nobuo Kato, Kunihiro Kaihatsu

Abstract:

A series of fatty acid monoester derivatives of (-)-epigallocatechin-3-O-gallate (EGCG) were prepared by one-pot lipase-catalyzed transesterification. The introduction of long alkyl chains enhanced anti-influenza A/PR8/34 (H1N1) virus activity 24-fold relative to native EGCG.

 

Study Type : In Vitro Study

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