Eggplant flavonoids exhibit cholesterol-lowering activity in rats. - GreenMedInfo Summary
Hypolipidemic effect of flavonoids from Solanum melongena.
Plant Foods Hum Nutr. 1997;51(4):321-30. PMID: 9650725
Department of Biochemistry, University of Kerala, Kariavattom, Thiruvananthapuram, India.
Flavonoids extracted from the fruits of Solanum melongena (Brinjal) orally administered at a dose of 1 mg/100 g BW/day showed significant hypolipidemic action in normal and cholesterol fed rats. HMG CoA reductase activity was found to be enhanced, while activities of glucose-6-phosphate dehydrogenase and malate dehydrogenase were significantly reduced. Activities of lipoprotein lipase and plasma LCAT showed significant enhancement. A significant increase in the concentrations of hepatic and fecal bile acids and fecal neutral sterols was also observed indicating a higher rate of degradation of cholesterol.