[Effect of electroacupuncture of "Neiguan" (PC 6) on heart rate and plasma catecholamine contents in ventricular tachycardia rats].
Zhen Ci Yan Jiu.2009 Jun;34(3):180-2, 187. PMID: 19761112
OBJECTIVE: To observe the effect of electroacupuncture (EA) of "Neiguan" (PC 6) on heart rate (HR) and plasma catecholamine (CA) levels in ventricular tachycardia (VT) rats. METHODS: A total of 50 SD rats were randomly divided into normal control, sham-operation (sham), model, EA-PC 6 and EA-LU 7 groups, with 10 cases in each. VT model was established by intravenous injection of cesium chloride (CsCl) via femoral vein. Electrocardiogram (ECG) was recorded. EA (2 Hz/15 Hz, 1 mA) was separately applied to bilateral "Neiguan" (PC 6) and "Lieque" (LU 7) for 5 minutes, followed by collecting blood samples for detecting plasma norepinephrine (NE) and epinephrine (E) levels with fluorometric method. RESULTS: In comparison with normal control group, plasma NE and E contents in model group increased apparently (P < 0.01). Compared with model group, HR and plasma NE and E contents of EA-PC 6 group reduced significantly (P < 0.01), while those of EA-LU 7 had no apparent change (P > 0.05). CONCLUSION: EA of "Neiguan" (PC 6) can downregulate heart rate and plasma CA level in VT rats, which may contribute to its effect in relieving tachycardia.