Elm bark exhibits anti-angiogenic activity. - GreenMedInfo Summary
Anti-angiogenic activity of the methanol extract and its fractions of Ulmus davidiana var. japonica.
J Ethnopharmacol. 2007 Jun 13;112(2):406-9. Epub 2007 Mar 12. PMID: 17428629
College of Pharmacy, Sookmyung Women's University, Seoul 140-742, Republic of Korea.
This study aimed to elucidate anti-angiogenic activity of Ulmus davidiana var. japonica that has been widely used in folk medicine. The methanol extract (UDE) of Ulmus davidiana var. japonica concentration-dependently displayed a strong inhibition in the chick chorioallantoic membrane (CAM) angiogenesis. The n-butanol fraction of UDE and subsequent 30% MeOH subfraction were identified to be most responsible for the anti-angiogenic activity.