Emerging antitumor activities of the bitter melon. - GreenMedInfo Summary
Emerging antitumor activities of the bitter melon (Momordica charantia).
Curr Protein Pept Sci. 2018 Jun 21. Epub 2018 Jun 21. PMID: 29932035
Evandro Fei Fang
Bitter melon or bitter gourd (Momordica charantia) is a common vegetable in Asia and it is distinctive for its bitter taste. As an ingredient in folk medicine, research from different laboratories in recent years supports its potential medicinal applications with anti-tumor, anti-diabetic, anti-HIV activities in both in vitro and animal studies. In this short review, we summarize herein the recent progress in the antitumor aspect of bitter melon with a focus on the underlying molecular mechanisms. Further mechanistic studies as well as clinical trials are necessary to further verify its medicinal applications.