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Abstract Title:

Hydroethanolic extracts from different genotypes of açaí (Euterpe oleracea) presented antioxidant potential and protected human neuron-like cells (SH-SY5Y).

Abstract Source:

Food Chem. 2017 May 1 ;222:94-104. Epub 2016 Dec 7. PMID: 28041564

Abstract Author(s):

Priscila do Carmo Marchioro Raupp Torma, Allana Von Sulzback Brasil, Ana Vânia Carvalho, André Jablonski, Thallita Kelly Rabelo, José Cláudio Fonseca Moreira, Daniel Pens Gelain, Simone Hickmann Flôres, Paula Rossini Augusti, Alessandro de Oliveira Rios

Article Affiliation:

Priscila do Carmo Marchioro Raupp Torma

Abstract:

Fruit breeding programs have resulted in bioactive compounds increase and health effects. Thus, this study aimed to evaluate the antioxidant activity and neuroprotective effects of the hydroethanolic extracts from six açaí (Euterpe oleracea) genotypes using ABTS, deoxyribose, and glutathione oxidation assays, as well as, SH-SY5Y cells insulted with H2O2. L22P13 genotype showed the highest total content of anthocyanins, while L06P13 showed a high content of total carotenoids. However, the genotypes showed no difference in the antioxidant activity by ABTS and deoxyribose assays. The hydroethanolic extracts from different genotypes of açaí showed a protective effect (13-62%) on SH-SY5Y cells insulted by H2O2 at a concentration of 50μg/mL by DCFH-DA assay. Except L04P16, no genotypes showed cytotoxicity inthe SRB assay. These results indicate that açaí genotypes have antioxidant effect against reactive species generated in SH-SY5Y cells, suggesting a neuroprotective effect of the hydroethanolic extracts from these fruits.

Study Type : In Vitro Study

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