Gastric polyposis has been reported due to treatment with proton pump inhibitors. - GreenMedInfo Summary
[Gastric polyposis due to treatment with proton pump inhibitors].
Gastroenterol Hepatol. 2009 Feb;32(2):88-91. Epub 2009 Feb 5. PMID: 19231680
Servicio de Patología Digestiva, Hospital General Universitario de Valencia, Valencia, España. [email protected]
Fundic gland polyps can appear sporadically or in association with familial adenomatous polyposis syndrome. An association between fundic gland polyps and prolonged treatment with proton pump inhibitors has been described, as has their regression after withdrawal of these inhibitors. Dysplastic components are not usually associated. We describe four patients who were receiving chronic treatment with proton pump inhibitors. The results of prior endoscopic analysis were normal. The presence of multiple fundic gland polyps was detected as was their disappearance 6 months after treatment cessation.