Gastro-protective potentials of spirulina: Role of vitamin B12. - GreenMedInfo Summary

Gastric ulcer is a chronic health problem world overis known to contain significant amounts of vitamin Bhencewas evaluated for gastroprotective properties against gastric ulcerations.biomass (SB) andextract (SE) were evaluated in swim stress induced gastric ulcers in adult male albino rats. Both SB and SE inhibited 45% and 60% of ulcers formation induced by swim stress respectively. Gastroprotection has been elucidated to be due to inhibition of (a) upregulated H, K-ATPase activity that induced ulcer condition; (b) lipid peroxidation and (c) altered antioxidant enzyme levels. The data highlighted the importance of vitamin Bin protecting the gut against gastric ulcerations and suggested that bothbiomass andextract contain bioavailable B.based product/food can be used as alternatives to gastroprotective agents that are known to cause acidity themselves upon long term use.