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Abstract Title:

Molecular characterization and dynamic expression patterns of two types ofγ-gliadin genes from Aegilops and Triticum species.

Abstract Source:

Theor Appl Genet. 2012 Jun 30. Epub 2012 Jun 30. PMID: 22751951

Abstract Author(s):

Shunli Wang, Xixi Shen, Pei Ge, Jie Li, Saminathan Subburaj, Xiaohui Li, F J Zeller, S L K Hsam, Yueming Yan

Article Affiliation:

Key Laboratory of Genetics and Biotechnology, College of Life Science, Capital Normal University, Beijing, 100048, China.

Abstract:

Gliadins were the major components of wheat storage proteins and determine the extensibility properties of gluten dough. In this work, 19 new full-lengthγ-gliadin genes were isolated from various Aegilops and Triticum species. Sequence characterization showed that a specific octapeptide and celiac disease (CD)-toxic epitope Gliγ-3 (VQGQGIIQPQQPAQL) were present in the rich glutamine domain and C-terminal non-repetitive domain, respectively. Basedon the sequence features of both peptides, a new classification system for γ-gliadin gene family was established, in which γ-gliadins were classified into two types (types I and II) with each consisting of two groups. An uneven distribution of different types and groups of γ-gliadin genes was exhibited among 11 Aegilops and Triticum genomes. Phylogenetic analysis revealed that types I and II genes diverged at about 14 MYA while the divergence of 4 γ-gliadin group genes occurred at around 10 MYA almost simultaneously. The γ-gliadin genes from S(l) and B genomes displayed a different transcriptional expression pattern during grain development, and rapid increasing of gliadin mRNA and proteins occurred at 15-20 DPA. In addition, genome-specific variations of CD-toxic epitopes among Aegilops and Triticum genomes were found. The A genome and its related progenitor genomes A(u) and A(m)had fewer CD epitopes than other genomes, suggesting that these genomes might be valuable gene resources to remove CD toxic peptides for wheat quality improvement.

Study Type : Plant Study
Additional Links
Problem Substances : Gliadin : CK(819) : AC(116)

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