Abstract Title:

Zingiber officinale Improves Cognitive Function of the Middle-Aged Healthy Women.

Abstract Source:

Evid Based Complement Alternat Med. 2012 ;2012:383062. Epub 2011 Dec 22. PMID: 22235230

Abstract Author(s):

Naritsara Saenghong, Jintanaporn Wattanathorn, Supaporn Muchimapura, Terdthai Tongun, Nawanant Piyavhatkul, Chuleratana Banchonglikitkul, Tanwarat Kajsongkram

Article Affiliation:

Neuroscience Program and Graduate School, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.

Abstract:

The development of cognitive enhancers from plants possessing antioxidants has gained much attention due to the role of oxidative stress-induced cognitive impairment. Thus, this study aimed to determine the effect of ginger extract, or Zingiber officinale, on the cognitive function of middle-aged, healthy women. Sixty participants were randomly assigned to receive a placebo or standardized plant extract at doses of 400 and 800 mg once daily for 2 months. They were evaluated for working memory and cognitive function using computerized battery tests and the auditory oddball paradigm of event-related potentials at three different time periods: before receiving the intervention, one month, and two months. We found that theginger-treated groups had significantly decreased P300 latencies, increased N100 and P300 amplitudes, and exhibited enhanced working memory. Therefore, ginger is a potential cognitive enhancer for middle-aged women.

Study Type : Human Study

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