Abstract Title:

Insulin resistance and adolescent girls with polycystic ovary syndrome.

Abstract Source:

J Pediatr Adolesc Gynecol. 2010 Jun ;23(3):158-61. Epub 2009 Dec 5. PMID: 19963413

Abstract Author(s):

S M Bhattacharya, M Ghosh

Article Affiliation:

S.C. Das Memorial Medical&Research Center and Vivekananda Institute of Medical Sciences, Kolkata, India. drsudhindra54@gmail.com

Abstract:

STUDY OBJECTIVES: To estimate (1) the prevalence of insulin resistance (IR), by fasting glucose: insulin ratio (G:I<7.0) in adolescent girls with polycystic ovary syndrome (PCOS), (2) to compare the clinical and biochemical parameters between insulin-resistant and non-insulin resistant groups.

DESIGN: Case series.

SETTING: Clinic based.

PARTICIPANTS: 49 adolescent girls with complaints of oligomenorrhoea with hirsutism and or acne.

INTERVENTIONS: Forty-nine adolescent girls diagnosed to have PCOS (Rotterdam 2003 criteria) were studied. Body mass index (BMI), abdominal circumference (AC), hirsutism (Ferriman Gallway score>or = 6), presence of acne, acanthosis nigricans (AN) were noted in each case. Serum testosterone, sex hormone binding globulin (SHBG), fasting plasma glucose and insulin levels were measured. Free androgen index (FAI) was calculated.

RESULTS: 69.4% of these girls were found to have IR. There were no differences in age, BMI, AC, serum testosterone, FAI and fasting glucose levels between insulin resistant and non-insulin resistant girls. But there were significant differences in frequencies of hirsutism, acne, AN, and serum levels of SHBG and fasting insulin between the two groups.

CONCLUSION: Adolescent girls with PCOS and IR are more hirsute and have more AN and lower SHBG and higher fasting insulin levels compared to non-insulin resistant girls.

Study Type : Human Study

Print Options


Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2020 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.