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Abstract Title:

Efficacy of gamma-linolenic acid in the treatment of patients with atopic dermatitis.

Abstract Source:

J Int Med Res. 1997 Sep-Oct;25(5):266-74. PMID: 9364289

Abstract Author(s):

M Andreassi, P Forleo, A Di Lorio, S Masci, G Abate, P Amerio

Abstract:

Full Citation: "Of 60 patients with atopic dermatitis (30 males and 30 females, 15-30 years old) 30 were treated with gamma-linolenic acid of (C18:3 n-6) at a dosage of 274 mg twice a day; the other 30 patients were given placebo. The patients were treated for 12 weeks, during which their symptoms were assessed on a linear scale both by a dermatologist and by themselves every 4 weeks. The patients who received gamma-linolenic acid, showed gradual improvements in pruritus, erythema, vesiculation and oozing, which were statistically significant compared with the control group (P < 0.001). Only one patient had presented with scaling at the beginning of the study and this symptom appeared to be less influenced by the effects of gamma-linolenic acid. The assessments of symptoms made by the dermatologist were generally consistent with those made by the patients themselves. gamma-linolenic acid was found to be effective and without side-effects for the treatment of atopic dermatitis.."

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Sayer Ji
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