Abstract Title:

Antioxidant effect of polyphenolic glabridin on LDL oxidation.

Abstract Source:

Toxicol Ind Health. 2009 May;25(4-5):321-4. PMID: 19651803

Abstract Author(s):

E Carmeli, Y Fogelman


This study was conducted to determine the effect of a natural polyphenolic isoflavone antioxidant (Glabridin) on low-density lipoprotein (LDL) oxidation. Determination of the extent of LDL oxidation was done by measuring the formation of Thiobarbituric acid reactive substances (TBARS). After oral administration of licorice-root ethanol extract to healthy subjects for 6 months, the subjects' oxidative stress level as well as plasma LDL oxidation reduced by 20%. We concluded that dietary consumption of glabridin protects LDL from oxidation.

Study Type : Human Study

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