Abstract Title:

Antioxidant activities of some common ingredients of traditional chinese medicine, Angelica sinensis, Lycium barbarum and Poria cocos.

Abstract Source:

Phytother Res. 2004 Dec;18(12):1008-12. PMID: 15742346

Abstract Author(s):

Sue-Jing Wu, Lean-Teik Ng, Chun-Ching Lin

Article Affiliation:

Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung, Taiwan.

Abstract:

The antioxidant activities of three popular ingredients of traditional Chinese medicine, namely Angelica sinensis (AS), Lycium barbarum (LB) and Poria cocos (PC) were evaluated in this study. The results showed that aqueous extracts of these crude drugs exhibited antioxidant activities in a concentration-dependent manner. All extracts displayed an inhibitory effect on FeCl2-ascorbic acid induced lipid peroxidation in rat liver homogenate in vitro, with the order of activity LB>AS>PC. The tested extracts showed a superoxide anion scavenging activity ranging from 28.8% to 82.2% and anti-superoxide activity varying from 38.0% to 84.5%. Among the different extracts, LB extract exhibited the lowest IC50 values (0.77-2.55 microg/mL) in all model systems tested in this study. The present study concludes that LB extract possessed the strongest inhibition on malondialdehyde formation in rat liver homogenate, and superoxide anion scavenging and anti-superoxide formation activities. These results also suggest that LB extract is a good source of antioxidant agent in the daily dietary supplement.

Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Antioxidants : CK(14410) : AC(5758)

Print Options


Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2020 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.