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Abstract Title:

Antiproliferative activity of Greek propolis.

Abstract Source:

J Med Food. 2010 Feb 4. Epub 2010 Feb 4. PMID: 20132046

Abstract Author(s):

Harris Pratsinis, Dimitris Kletsas, Eleni Melliou, Ioanna Chinou

Abstract:

Abstract The butanolic extract and the isolated chemical constituents, mainly diterpenes and flavonoids, from Greek propolis have been tested for their cytostatic activities against human malignant and normal cell strains. The extract and the diterpenes were found to be the most active against HT-29 human colon adenocarcinoma cells, without affecting normal human cells. Manool, a diterpene isolated for the first time from Greek propolis, was the most active compound, arresting the cancer cells at the G(2)/M phase of the cell cycle.

Study Type : In Vitro Study

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Sayer Ji
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