Harmine induces apoptosis in human SGC-7901 cells. - GreenMedInfo Summary
[Harmine induces apoptosis in human SGC-7901 cells].
Zhong Yao Cai. 2006 Jun ;29(6):571-3. PMID: 17039880
OBJECTIVE: [corrected] To investigate the effect of apoptosis induced in human SGC-7901 cells by Harmine.
METHODS: The effect of Harmine on human SGC-7901 cell survival and apoptosis was determined by MTT assay, light microscopy and flow cytometry. Cell genomic DNA was detected by agarose electrophoresis.
RESULTS: The survival of human SGC-7901 cells decreased; Apoptotic cells were observed by fluorescent microscope; FCM analysis showed that the peak of apoptosis increased. Typical DNA Ladder were detected in DNA agarose gel electrophoresis.
CONCLUSION: HM can induce apoptosis in human SGC-7901 cells.