Abstract Title:

Health-promoting effects of the citrus flavanone hesperidin.

Abstract Source:

Crit Rev Food Sci Nutr. 2017 Feb 11 ;57(3):613-631. PMID: 25675136

Abstract Author(s):

Chaoyun Li, Hermann Schluesener

Article Affiliation:

Chaoyun Li


Hesperidin, a member of the flavanone group of flavonoids, can be isolated in large amounts from the rinds of some citrus species. Considering the wide range of pharmacological activities and widespread application of hesperidin, this paper reviews preclinical and clinical trials of hesperidin and its related compounds, including their occurrence, pharmacokinetics, and some marketed products available. Preclinical studies and clinical trials demonstrated therapeutical effects of hesperidin and its aglycone hesperetin in various diseases, such as neurological disorders, psychiatric disorders, and cardiovascular diseases and others, due to its anti-inflammatory, antioxidant, lipid-lowering, and insulin-sensitizing properties.

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