n/a
Article Publish Status: FREE
Abstract Title:

Heat stability of the in vitro inhibitory effect of spices on lipase, amylase, and glucosidase enzymes.

Abstract Source:

Food Sci Nutr. 2019 Feb ;7(2):425-432. Epub 2019 Jan 28. PMID: 30847119

Abstract Author(s):

Irushika T Fernando, Kumudu I Perera, Senarath B P Athauda, Ramiah Sivakanesan, Nimal Savitri Kumar, Lalith Jayasinghe

Article Affiliation:

Irushika T Fernando

Abstract:

This study investigated the effect of boiling on the inhibitory action of spices on digestive enzymes. Unboiled extracts of(seed) (25.42%),(seed) (22.70%), and(seed) (19.17%) showed significantly (<0.05) a higher lipase inhibitory activity than their respective boiled extracts (20.23%, 15.74%, and 12.57%). Unboiled extracts of(stem bark) (-16.98%) and(seed) (-16.05%) showed an activation of lipase enzyme, and boiling significantly (<0.05) changed the activity into lipase inhibition as 8.47% and 9.54%, respectively. Unboiled extracts of(seed), and(seed) showed an activation of amylase enzyme, and boiling these extracts significantly reduced the enzyme activation. The other unboiled extracts showed a higher amylase inhibition than the boiled extracts, whereas the boiled extracts of(rhizome) and(flower) exhibited significantly (<0.05) lower values. Unboiled extracts of,, andshowed an insignificantly higher glucosidase inhibitory activity than the boiled extracts. Inhibition of digestive enzymes by nutritional intervention is one avenue to be considered in treating diet-induced obesity and in the management of postprandial hyperglycemia. Spices, used as food additives, could be a potential source of digestive enzyme inhibitors. The current study revealed that unboiled extracts of(seed),(seed), and(seed) are more effective than the boiled extracts as an antiobesity therapy. Moreover, it endorses the use of infusion ofseeds as an antiobesity therapy.

Print Options


Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2020 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.