Abstract Title:

Antimutagenic and anticancer activity of Al Madinah Alhasawy mint (Mentha longifolia) leaves extract.

Abstract Source:

Pak J Biol Sci. 2014 Dec ;17(12):1231-6. PMID: 26027170

Abstract Author(s):

Khalil Al-Ali, Mohamad Abdelrazik, Abdulaziz Alghaithy, Atef Diab, Hesham El-Beshbishy, Hussam Baghdadi

Article Affiliation:

Khalil Al-Ali

Abstract:

Mentha is one of the genera of Lamiaceae family. The aim of the present study was to evaluate the antimutagenic and anticancer activity of the water and methanolic extract of Alhasawy mint (Mentha longifolia), that grown in Madina Province, western region, Saudi Arabia using three different bioassays namely; Brine shrimp bioassay, Ames mutagenicity bioassay using 3 Hist-Salmonella typhimurium strains of different mutations (TA98, TA97 and TA100) and 2 reference mutagenic drugs nitrosopiperidine (NP) and 2-amino-3-methylimidazo-quinolidine (IQ) and Mammalian cell lines bioassays using 2 different cell lines HepG2 and Vero cell lines. The plant extract showed an efficient antimutagenic activity against the studied bioassays in a directly proportional effect with concentration.

Study Type : In Vitro Study

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