Hyperamylasemia due to macroamylasemia in adult gluten enteropathy has been reported. - GreenMedInfo Summary
Hyperamylasemia due to macroamylasemia in adult gluten enteropathy.
Scand J Clin Lab Invest. 1997 May ;57(3):271-3. PMID: 9238763
Department of Clinical Biochemistry, University of Pavia, Policlinico San Matteo, Italy.
We report hyperamylasemia due to macroamylasemia in a 33-year-old-woman with gluten enteropathy. Macroamylasemia was demonstrated by precipitation of 97% of amylase activity with PEG 6000. It was associated with increased serum IgA, with elevated values of specific IgA antibodies against alpha-gliadin and with a high titre of IgA anti-endomysium antibodies. Macroamylasemia disappeared after 2 months of a strict gluten-free diet. These data suggest that the increased IgA concentration in adult gluten enteropathy led to increased macroamylase formation.