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Abstract Title:

Hypoglycemic and antioxidant effects of five commercial turmeric (Curcuma longa) supplements.

Abstract Source:

J Food Biochem. 2020 Jul 21:e13389. Epub 2020 Jul 21. PMID: 32691874

Abstract Author(s):

Fernando Guerrero-Romero, Luis E Simental-Mendía, Gerardo Martínez-Aguilar, Miguel A Sánchez-Meraz, Claudia I Gamboa-Gómez

Article Affiliation:

Fernando Guerrero-Romero

Abstract:

We evaluate the hypoglycemic and antioxidant effects of five commercial turmeric (Curcuma longa) supplements: (1) bulk samples, (2) turmeric root from India, (3) curcuma turmeric Pronat, (4) turmeric&black pepper Swanson, and (5) C3 complexturmeric curcumin. Glucose diffusion and enzymatic starch digestion assays, usingα-amylase and α-glucosidase, were performed. The antioxidant activity of turmeric supplements was measured through lipid peroxidation inhibition and the scavenging radical assay. A starch dose of 102 mg/Kg of body weight (equivalent to 1 g/day in humans) was used to perform the oral starch tolerance test (OSTT) in Wistar male rats. All turmeric supplements decreased glucose diffusion and α-glucosidase enzyme activity, and inhibited lipid peroxidation. The rats that received bulk samples and CT showed significantly lower glucose levels than rats receiving acarbose and those of negative control group. Our results show that biological activities of turmeric supplements vary according to the commercial presentation. PRACTICAL APPLICATIONS: The study results suggest that the hypoglycemic and antioxidant effects of five commercial turmeric supplements vary among them. The information provided would be useful to physicians and individuals using these supplements.

Study Type : In Vitro Study

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