Abstract Title:

Immunomodulatory actions of a Polynesian herb Noni (Morinda citrifolia) and its clinical applications.

Abstract Source:

Complement Ther Med. 2019 Dec ;47:102206. Epub 2019 Oct 3. PMID: 31780035

Abstract Author(s):

Madhukar Lohani, Mohammed Majrashi, Manoj Govindarajulu, Mansi Patel, Sindhu Ramesh, Dwipayan Bhattacharya, Sneha Joshi, Maali Fadan, Rishi Nadar, Benjamin Darien, Denzil V Maurice, Barbara Kemppainen, Muralikrishnan Dhanasekaran

Article Affiliation:

Madhukar Lohani


Morinda citrifolia (Noni) is a popular traditional medicinal plant consumed in various forms in several countries around the world as a complementary and alternative treatment due to its established health benefits. Noni is rich in bioactive substances and has significantly exhibited pro-oxidant and immunomodulatory effects. In this review, we highlight the pharmacological basis related to the phytochemicals and polysaccharides present in Noni and its potential therapeutic effects. We screened electronic databases such as PubMed, Google Scholar, Scopus for scientific literature. Our results indicate that Noni is beneficial for various diseases with its crude extracts showing therapeutic benefit for a wide range of pathological diseases. We believe that further pharmacological and toxicological studies in addition to well-designed controlled clinical trials can validate Noni to be an effective and novel natural product for prophylactic and therapeutic use of several diseases.

Study Type : Review

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