Article Publish Status: FREE
Abstract Title:

Impact of air pollution exposure during various periods of pregnancy on term birth weight: a large-sample, retrospective population-based cohort study.

Abstract Source:

Environ Sci Pollut Res Int. 2021 Jan ;28(3):3296-3306. Epub 2020 Sep 11. PMID: 32914309

Abstract Author(s):

Li Shang, Liyan Huang, Liren Yang, Longtao Leng, Cuifang Qi, Guilan Xie, Ruiqi Wang, Leqian Guo, Wenfang Yang, Mei Chun Chung

Article Affiliation:

Li Shang


Previous studies have suggested that maternal exposure to air pollution might affect term birth weight. However, the conclusions are controversial. Birth data of all term newborns born in Xi'an city of Shaanxi, China, from 2015 to 2018 and whose mother lived in Xi'an during pregnancy were selected form the Birth Registry Database. And the daily air quality data of Xi'an city was collected from Chinese Air Quality Online Monitoring and Analysis Platform. Generalized additive models (GAM) and 2-level binary logistic regression models were used to estimate the effects of air pollution exposure on term birth weight, the risk term low birth weight (TLBW), and macrosomia. Finally, 321521 term newborns were selected, including 4369(1.36%) TLBW infants and 24,960 (7.76%) macrosomia. The average pollution levels of PM, PM, and NOin Xi'an city from 2015 to 2018 were higher than national limits. During the whole pregnancy, maternal exposure to PM, PM, SO, and CO all significantly reduced the term birth weight and increased the risk of TLBW. However, NOand Oexposure have significantly increased the term birth weight, and Oeven increased the risk of macrosomia significantly. Those effects were also observed in the first and second trimesters of pregnancy. But during the third trimester, high level of air quality index (AQI) and maternal exposure to PM, PM, SO, NO, and CO increased the term birth weight and the risk of macrosomia, while Oexposure was contrary to this effect. The findings suggested that prenatal exposure to air pollution might cause adverse impacts on term birth weight, and the effects varied with trimesters and pollutants, which provides further pieces of evidence for the adverse effects of air pollution exposure in heavy polluted-area on term birth weight.

Study Type : Human Study

Print Options

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2021 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.