Abstract Title:

Mediterranean diet and colorectal cancer risk: a pooled analysis of three Italian case-control studies.

Abstract Source:

Br J Cancer. 2016 Aug 18. Epub 2016 Aug 18. PMID: 27537381

Abstract Author(s):

Valentina Rosato, Valentina Guercio, Cristina Bosetti, Eva Negri, Diego Serraino, Attilio Giacosa, Maurizio Montella, Carlo La Vecchia, Alessandra Tavani

Article Affiliation:

Valentina Rosato

Abstract:

BACKGROUND: Adherence to the Mediterranean diet (MD) is associated with a reduced risk of several cancers. However, studies conducted in Mediterranean regions are scanty.

METHODS: To investigate the relation between MD and colorectal cancer risk in Italy, we pooled data from three case-control studies, including a total of 3745 colorectal cancer cases and 6804 hospital controls. Adherence to the MD was assessed using an a priori Mediterranean Diet Score (MDS), based on nine components.

RESULTS: Compared with the lowest adherence to the MD (0-2 MDS), the odds ratio (OR) was 0.52 (95% confidence interval (CI) 0.43-0.62) for the highest adherence (7-9 MDS), with a significant inverse trend in risk (P<0.0001). The OR for a 1-point increment in the MDS was 0.89 (95% CI 0.86-0.91). The inverse association was consistent across studies, cancer anatomical subsites and strata of selected covariates.

CONCLUSIONS: This Italian study confirms a favourable role of MD on colorectal cancer risk.British Journal of Cancer advance online publication, 18 August 2016; doi:10.1038/bjc.2016.245 www.bjcancer.com.

Study Type : Human Study

Print Options


Key Research Topics

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2024 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.