Abstract Title:

[Effect of blastolysin on the development of specific immunity to whooping cough].

Abstract Source:

Zh Mikrobiol Epidemiol Immunobiol. 1986 Jan;(1):62-5. PMID: 3705806

Abstract Author(s):

I B Shepeleva, N S Zakharova, T N Remova, I G Bazhanova, M V Britsina


The influence of blastolysin, the cell-wall glycopeptide of Lactobacillus bulgaricus, on the main immunobiological properties of pertussis vaccine, its immunogenicity and toxicity, has been studied. The use of blastolysin, introduced as a stimulating agent in definite doses and following definite administration schedules, has been shown to permit achieving not only an increase in the immunogenicity of the corpuscular pertussis vaccine, but also a considerable decrease in its toxicity and histamine-sensitizing activity.

Study Type : Animal Study

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