Abstract Title:

Antimicrobial potential of Glycyrrhiza glabra roots.

Abstract Source:

J Altern Complement Med. 2010 May;16(5):555-60. PMID: 18182260

Abstract Author(s):

Vivek K Gupta, Atiya Fatima, Uzma Faridi, Arvind S Negi, Karuna Shanker, J K Kumar, Neha Rahuja, Suaib Luqman, Brijesh S Sisodia, Dharmendra Saikia, M P Darokar, Suman P S Khanuja

Abstract:

The present study was aimed to investigate antimicrobial potential of Glycyrrhiza glabra roots. Antimycobacterial activity of Glycyrrhiza glabra was found at 500 microg/mL concentration. Bioactivity guided phytochemical analysis identified glabridin as potentially active against both Mycobacterium tuberculosis H(37)Ra and H(37)Rv strains at 29.16 microg/mL concentration. It exhibited antimicrobial activity against both Gram-positive and Gram-negative bacteria. Our results indicate potential use of licorice as antitubercular agent through systemic experiments and sophisticated anti-TB assay.

Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Antimycobacterial : CK(35) : AC(19)

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