Effects of selenium and light wavelengths on liquid culture of Cordyceps militaris Link.
Appl Biochem Biotechnol. 2012 Apr ;166(8):2030-6. Epub 2012 Mar 21. PMID: 22434354
J Z Dong
To investigate the effects of selenium and light wavelengths on the growth of liquid-cultured Cordyceps militaris and the main active components' accumulation, culture conditions as selenium selenite concentrations and light of different wavelengths were studied. The results are: adenosine accumulation proved to be significantly selenium dependent (R(2) = 0.9403) and cordycepin contents were determined to be not significantly selenium dependent (R(2) = 0.3845) but significantly enhanced by selenium except for 20 ppm; there were significant differences in cordycepin contents, adenosine contents, and mycelium growth caused by light wavelengths: cordycepin, blue light>pink light>daylight, darkness, red light; adenosine, red light>pink light, darkness, daylight, blue light; and mycelium growth, red light>pink light, darkness, daylight>blue light. In conclusion, light wavelength had a significant influence on production of mycelia, adenosine, and cordycepin, so lightening wavelength should be changed according to target products in the liquid culture of C. militaris.