Low HDL cholesterol is a risk factor for deficit and decline in memory in midlife. - GreenMedInfo Summary
Low HDL cholesterol is a risk factor for deficit and decline in memory in midlife: the Whitehall II study.
Arterioscler Thromb Vasc Biol. 2008 Aug;28(8):1556-62. Epub 2008 Jun 30. PMID: 18591462
INSERM U687-IFR69, Hôpital Paul Brousse, Bât 15/16, 16 Avenue Paul Vaillant Couturier, 94807 Villejuif Cedex, France. Archana.Singh-Manoux@inserm.fr
OBJECTIVE: The purpose of this study was to examine the relationship between fasting serum lipids and short-term verbal memory in middle-aged adults. METHODS AND RESULTS: Total cholesterol, high-density lipoprotein cholesterol (HDL-C), triglycerides, and memory were measured twice, at mean ages 55 and 61, in 3673 male and female participants of the Whitehall II study. Short-term verbal memory was assessed using a 20-word list. Logistic regression was used to model associations between ATP-III categories of lipids and memory deficit (recall of