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Article Publish Status: FREE
Abstract Title:

Lycopene improves on basic hematological and immunological parameters in diabetes mellitus.

Abstract Source:

BMC Res Notes. 2019 Dec 12 ;12(1):805. Epub 2019 Dec 12. PMID: 31831054

Abstract Author(s):

Ejike Daniel Eze, Adam Moyosore Afodun, Josephine Kasolo, Keneth Iceland Kasozi

Article Affiliation:

Ejike Daniel Eze

Abstract:

OBJECTIVE: Diabetes is associated with an upset of hematological and immunological parameters in humans, however information on the effects of Lycopene is scarce. The aim of the study was to gain information on basic changes in hematological parameters as markers for safety since anemia as a complication in diabetic chemotherapy has been reported.

RESULTS: Lycopene had anti-anemic effects and improved on the immune status of diabetic rats and these observations were dose independent. There was a decrease in neutrophil, low neutrophil-lymphocyte ratio and platelet counts and stable albumin, globulin levels. Lycopene could exert its protective effects through a balance of basic hematological physiological variables.

Study Type : Animal Study

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