M. alba can effectively contribute to the reduction in postprandial glucose levels. - GreenMedInfo Summary
A meta-analysis of efficacy of Morus alba Linn. to improve blood glucose and lipid profile.
Eur J Nutr. 2016 Mar 14. Epub 2016 Mar 14. PMID: 26972284
PURPOSE: The previous studies have reported the Morus alba may improve blood glucose and lipid profile. The evidence from these studies is not consistent. This meta-analysis was to evaluate efficacy of products derived from M. alba on blood glucose and lipid levels.
METHODS: Literature was reviewed via international database (PubMed, PubMed Central, ScienceDirect, and SciSearch) and Thai databases. Thirteen RCTs with high quality, assessed by Jadad score, were included.
RESULTS: M. alba expressed a significant reduction in postprandial glucose (PPG) at 30 min (MD -1.04, 95 % CI -1.36, -0.73), 60 min (MD -0.87, 95 % CI -1.27, -0.48) and 90 min (MD -0.55, 95 % CI -0.87, -0.22). The difference was not found in the levels of other glycaemic (FBS, HbA1C, or HOMA-IR) and lipidaemic (TC, TG, LDL, or HDL) markers. Serious adverse effects were found neither in the control nor in the group received M. alba.
CONCLUSION: Products derived from M. alba can effectively contribute to the reduction in PPG levels, but large-scale RCTs would be informative.