Article Publish Status: FREE
Abstract Title:

Magnesium Supplementation Shortens Hemodialysis-Associated Prolonged QT.

Abstract Source:

Cureus. 2020 Jul 11 ;12(7):e9132. Epub 2020 Jul 11. PMID: 32670733

Abstract Author(s):

Krishna Kishore Umapathi, Sunah Lee, Jessica Jacobson, Sara Jandeska, Hoang H Nguyen

Article Affiliation:

Krishna Kishore Umapathi


Hemodialysis affects myocardial depolarization and repolarization notably lengthening the QT interval. Prolonged QT, in turn, has been a reliable surrogate for higher risk of potentially lethal ventricular arrhythmias. We present an adolescent girl with end-stage kidney disease who consistently developed prolonged QT following hemodialysis sessions. Interestingly, her QT intervals were inversely correlated with her serum magnesium levels. Magnesium supplementation appeared to help reduce the QT prolongation after hemodialysis. Our case shows the potential utility of magnesium as a cardioprotective agent in hemodialysis patients. We recommend that patients undergoing hemodialysis receive frequent electrocardiograms and electrolytes monitoring for tailored electrolytes management to reduce the risk of developing potentially lethal cardiac arrhythmias.

Study Type : Human: Case Report
Additional Links
Pharmacological Actions : Cardioprotective : CK(5377) : AC(1675)

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