Maternal anaphylaxis and fetal brain damage after intrapartum chemoprophylaxis.
J Perinat Med. 2004;32(4):375-7. PMID: 15346827
Neonatal Intensive Care Unit, Azienda Policlinico, Modena, Italy. [email protected]
We report a case of maternal anaphylaxis following intrapartum chemoprophylaxis. The term fetus developed severe brain damage as a consequence of intrapartum asphyxia. The lesions resulted from maternal hypotension following anaphylaxis. We discuss the feto-maternal risks and the controversial treatment of such a condition. The increasing number of penicillin-treated parturients will result in further cases of maternal anaphylaxis than previously found.