Tea tree oil as a novel antipsoriasis weapon.
Skin Pharmacol Physiol. 2012 ;25(3):162-3. Epub 2012 Apr 3. PMID: 22473218
Department of Dermatology, Jundishapur University of Medical Sciences, Ahvaz, Iran.
Psoriasis is a clinical skin disease that is characterized by erythematous scaling plaques and involves the extensor site of the extremities, the scalp and other surfaces of the skin. Tea tree oil (TTO) is considered an essential oil, obtained by steam distillation of the leaves and terminal branchlets of Melaleuca alternifolia. Notably,terpinen-4-ol, the major TTO constituent, has been found to have potent anti-inflammatory properties. It is suggested that terpinen-4-ol may be a novel potential agent against psoriasis. This article draws attention to the antipsoriatic effect of TTO and provides a theoretical molecular approach.