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Abstract Title:

Effects of melatonin on cardiovascular diseases: progress in the past year.

Abstract Source:

Curr Opin Lipidol. 2016 Apr 12. Epub 2016 Apr 12. PMID: 27075419

Abstract Author(s):

Hang Sun, Aaron M Gusdon, Shen Qu

Article Affiliation:

Hang Sun

Abstract:

PURPOSE OF REVIEW: Melatonin is a neuroendocrine hormone synthesized primarily by the pineal gland. Numerous studies have suggested that melatonin plays an important role in various cardiovascular diseases. In this article, recent progress regarding melatonin's effects on cardiovascular diseases is reviewed.

RECENT FINDINGS: In the past year, studies have focused on the mechanism of protection of melatonin on cardiovascular diseases, including myocardial ischemia-reperfusion injury, myocardial hypoxia-reoxygenation injury, pulmonary hypertension, hypertension, atherosclerosis, valvular heart diseases, and other cardiovascular diseases.

SUMMARY: Studies have demonstrated that melatonin has significant effects on ischemia-reperfusion injury, myocardial chronic intermittent hypoxia injury, pulmonary hypertension, hypertension, valvular heart diseases, vascular diseases, and lipid metabolism. As an inexpensive and well tolerated drug, melatonin may be a new therapeutic option for cardiovascular disease.

Study Type : Review

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