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Abstract Title:

Mentha arvensis essential oil suppressed airway changes induced by histamine and ovalbumin in experimental animals.

Abstract Source:

Nat Prod Res. 2017 Apr 7:1-5. Epub 2017 Apr 7. PMID: 28385073

Abstract Author(s):

Shilpa Sharma, Vijaykumar P Rasal, Paragouda A Patil, Rajesh K Joshi

Article Affiliation:

Shilpa Sharma

Abstract:

The present investigation aimed to evaluate the activity of the essential oil of Mentha arvensis L. on exogenously induced bronchoconstriction in experimental animals. The anti-asthmatic effect of M. arvensis essential oil (MAEO) was studied using histamine aerosol-induced bronchoconstriction in guinea pigs and ovalbumin (OVA) sensitised albino mice. Treatment with M. arvensis oil significantly (p < 0.001) increased the time of preconvulsive dyspnoea in histamine-induced guinea pigs. Oral treatment of MAEO significantly (p < 0.001) decreased absolute eosinophil count, serum level of IgE and the number of eosinophils, neutrophils in BALF. Histopathological examination of lungs showed that essential oil rescinded bronchial asthma. The present investigation provides evidence that MAEO relaxes bronchial smooth muscles andsuppressed immunological response to OVA.

Study Type : Animal Study
Additional Links
Pharmacological Actions : Anti-Asthmatic Agents : CK(24) : AC(3)
Additional Keywords : Essential Oils : CK(181) : AC(69)

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