Abstract Title:

Metabolomics study of different parts of licorice from different geographical origins and their anti-inflammatory activities.

Abstract Source:

J Sep Sci. 2020 Apr ;43(8):1593-1602. Epub 2020 Feb 26. PMID: 32032980

Abstract Author(s):

Haiying Bai, Fang Bao, Xiaorui Fan, Shu Han, Wenhui Zheng, Lili Sun, Na Yan, Hong Du, Haiyu Zhao, Zhigang Yang

Article Affiliation:

Haiying Bai


Glycyrrhiza uralensis Fisch., known as licorice, is one of the most famous traditional Chinese medicines. In this study, we perform a metabolome analysis using liquid chromatography-tandem mass spectrometry to assign bioactive components in different parts of licorice from different geographical origins in Gansu province of China. Sixteen potential biomarkers of taproots from different geographical origins were annotated, such as glycycoumarin, gancaonin Z, licoricone, and dihydroxy kanzonol H mainly exist in the sample of Jiuquan; neoliquiritin, 6'-acetylliquiritin, licochalcone B, isolicoflavonol, glycyrol, and methylated uralenin mainly exist in Glycyrrhiza uralensis from Lanzhou; gancaonin L, uralenin, and glycybridin I mainly exist in licorice from Wuwei for the first time.

Study Type : In Vitro Study

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